There are several ways to implement sending and receiving messages from Azure Logic Apps, like using HTTP requests, and by doing so you can create robust and smart hybrid integrations. You may have to use one of these alternative implementations if you are using older versions of BizTalk Server.
The good news is that BizTalk Server 2016 has a better and more user-friendly way to make these hybrid connections. Instead of using HTTP requests, with BizTalk Server 2016 you can use the Logic Apps adapter to receive messages from an Azure Logic App, or send messages to an Azure Logic App.
By reading this whitepaper, decision makers should have more information on the following areas: